22 August 2016
Chinese scientists said they have discovered a small molecule that can regenerate tissues with ease.
Professores Zhou Dawang, Deng Xianming, of the School of Life Sciences, Xiamen University, and Yun Caihong of Peking University, the lead researches, disclosed this on Monday in Xiamen (China).
They said that the findings were published in the latest edition of Science Transnational Medicine, on Aug. 17, saying in the future, it could make tissue regeneration much easier for many.
Zhou said they have discovered a drug, XMU-MP-1, which can promote repair and regeneration in the liver, intestines and skin.
“In the future, the pills may do away the need for organ transplant or complex biomaterial and cell therapies.
Xianming said the he and his colleagues specifically targeted a critical signalling molecule in the Hippo pathway, which controls organ size.
He noted that the XMU-MP-1 has proven to inhibit the activity of MST1/2, the central component of this pathway and promote cell growth in four different mouse models of acute and chronic injuries.
Xianming said it included the acetaminophen-induced injury, which is a common cause of liver failure worldwide.
He added that they had applied for a patent and are cooperating with pharmaceutical companies to produce the medicine.